Galectin-3 as prognostic biomarker in patients with COVID-19 acute respiratory failure

Glycovirology

This study used galectin-3 serum levels upon hospitalization to predict 30 day mortality. Galectin-3 serum levels higher than 35.3 ng/ml was the cutoff point that predicted mortality, intensive care admission, or ARDS. A Galectin-3 cut-off of 35.3 ng/ml was fixed to achieve a sensitivity of 80% and a specificity of 92.1% for mortality prediction, with an AUC value of 0.906 (95% CI 0.85–0.96, p < 0.0001).

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